| Next Generation Manufacturing Canada CA-E-HCJ2-0BAR | Federal not-for-profit corporation | Active | Hamilton | $576.7M |
| Mcmaster University CA-E-BSDA-604X | Registered charity | Current | HAMILTON | $398.4M |
| Mohawk College Of Applied Arts & Technology CA-E-0WD1-SQQY | Registered charity | Former | HAMILTON | $140.1M |
| Wesley Urban Ministries INC. CA-E-MM55-4VF3 | Registered charity | Current | HAMILTON | $89.6M |
| Hamilton-wentworth Catholic District School Board CA-E-7NJQ-9B9E | Registered charity | Current | HAMILTON | $75.2M |
| Immigrants Working Centre (hamilton) CA-E-92RG-AQKK | Registered charity | Current | HAMILTON | $62.7M |
| Ymca Of Hamilton/burlington/brantford CA-E-4HX5-KKZ8 | Registered charity | Former | HAMILTON | $62.1M |
| Stryker Canada INC. CA-E-PFSZ-SJE8 | Federal corporation | Inactive | HAMILTON | $61.7M |
| Royal Botanical Gardens CA-E-Z3H4-GQN8 | Registered charity | Former | HAMILTON | $11.5M |
| Threshold School of Building CA-E-RVNF-MGCD | Registered charity | Active | HAMILTON | $10.6M |
| Amity Goodwill Industries CA-E-V5VS-FG9G | Registered charity | Current | HAMILTON | $8.0M |
| Today's Family - Caring For Your Child CA-E-9J7P-DRKN | Registered charity | Current | HAMILTON | $6.9M |
| Global Citizens Care For Underprivileged And Refugee Empowerment INC. CA-E-NN0R-NYT8 | Registered charity | Active | Hamilton | $5.3M |
| Art Gallery Of Hamilton CA-E-4FVF-AVD3 | Registered charity | Current | HAMILTON | $4.4M |
| Hamilton East Kiwanis Boys' & Girls' Club CA-E-3AE2-039V | Registered charity | Current | HAMILTON | $2.7M |
| Rygiel Supports For Community Living CA-E-P0S9-H8XD | Registered charity | Current | HAMILTON | $1.9M |
| Culture For Kids In The Arts CA-E-81PS-BVP3 | Registered charity | Current | HAMILTON | $1.2M |
| Mission Services of Hamilton Foundation CA-E-AS6G-XGMN | Registered charity | Active | HAMILTON | $1.1M |
| Indwell Community Homes CA-E-81J2-88PT | Registered charity | Current | HAMILTON | $1.1M |
| Ableliving Services INC. CA-E-D437-M3AV | Registered charity | Current | HAMILTON | $663K |
| Lift Church CA-E-868B-T2ZG | Registered charity | Active | Hamilton | $435K |
| Peoples Church Hamilton CA-E-K485-7P1P | Registered charity | Active | Hamilton | $280K |
| James North Baptist Church CA-E-WKKA-PKM2 | Registered charity | Active | Hamilton | $165K |
| House Of Praise And Prayer CA-E-4T3V-72W5 | Registered charity | Active | Hamilton | $97K |
| Somali Community in Hamilton CA-E-VG64-MC69 | Registered charity | Active | Hamilton | $92K |
| Westdale Cinema Group CA-E-P68Q-JYXJ | Registered charity | Active | Hamilton | $92K |
| De Mazenod Door Outreach CA-E-8DFA-K3YF | Registered charity | Active | Hamilton | $85K |
| Helping Hands Street Mission CA-E-1ZQ5-BBKB | Registered charity | Active | Hamilton | $79K |
| Donald Moore Community Services INC. CA-E-GYVP-ARAJ | Registered charity | Active | Hamilton | $75K |
| Galcom International Incorporated CA-E-SFZR-NWNP | Registered charity | Active | HAMILTON | $67K |
| International Needs Canada CA-E-ZCMF-4X8B | Registered charity | Active | Hamilton | $66K |
| Mount Hamilton Baptist Church CA-E-R27G-SAMD | Registered charity | Active | Hamilton | $65K |
| Eagle's Nest Association Of Waterdown CA-E-X4WZ-QCMN | Registered charity | Active | Hamilton | $63K |
| Eagle Worldwide Ministries CA-E-WFH0-70DJ | Registered charity | Active | Hamilton | $60K |
| Canadian Centre For Occupational Health And Safety CA-E-ZVR2-FPY7 | Registered charity | Active | HAMILTON | $56K |
| Family Councils of Ontario CA-E-RP3T-9SKX | Registered charity | Active | Hamilton | $53K |
| Body Brave Inc. CA-E-J081-P27N | Registered charity | Active | Hamilton | $51K |
| The Cardus Institute CA-E-G7QF-PYBG | Registered charity | Active | Hamilton | $50K |
| Eagle Worldwide Community Enrichment CA-E-XPW4-69M3 | Registered charity | Active | HAMILTON | $46K |
| Westside Church CA-E-PMND-6DMF | Registered charity | Active | Hamilton | $43K |
| Harmony Community Hub CA-E-0SAV-5FY4 | Registered charity | Active | Hamilton | $39K |
| Khayr Project Canada CA-E-7SFS-RNRM | Registered charity | Active | Hamilton | $37K |
| Eucharist Church Of Hamilton CA-E-TZEE-XMQ8 | Registered charity | Active | Hamilton | $33K |
| Shalom Village Foundation CA-E-19JT-32ND | Registered charity | Active | Hamilton | $29K |
| Helping International Students CA-E-4YGD-PMEJ | Registered charity | Active | Hamilton | $19K |
| Reborn For Christ CA-E-WFXP-B2HC | Registered charity | Active | Hamilton | $14K |
| Act Five Initiatives CA-E-K6XW-SWHM | Registered charity | Active | Hamilton | $14K |
| Church Underground Inc. CA-E-S9M9-DNM5 | Registered charity | Active | Hamilton | $14K |
| Atwell Centre: Pregnancy Options Support CA-E-2EVV-K8G5 | Registered charity | Active | Hamilton | $13K |
| Ymhc Charitable Foundation CA-E-DC42-B3CS | Registered charity | Active | Hamilton | $11K |
| Micah House Refugee Reception Services Inc. CA-E-5W4P-QDZ6 | Registered charity | Active | HAMILTON | $10K |
| The River International Church CA-E-B1CP-YCBM | Registered charity | Active | HAMILTON | $9K |
| Mission Baptist Church - Hamilton CA-E-DHGB-PXBA | Registered charity | Active | HAMILTON | $8K |
| Christians Against Poverty Canada CA-E-1G4K-KA4Y | Registered charity | Active | Hamilton | $6K |
| Jump In Foundation CA-E-1DSK-QSZH | Registered charity | Active | HAMILTON | $4K |