| Info-Tech Research Group Inc. CA-E-GT20-X3M8 | Federal corporation | Active | LONDON | $5.9B |
| The University Of Western Ontario CA-E-C5ZV-BDT3 | Registered charity | Former | LONDON | $760.0M |
| 3M Canada Limited CA-E-YFT6-A2XA | Federal corporation | Inactive | LONDON | $307.9M |
| Ivey Business School Foundation CA-E-VM3P-HCB8 | Registered charity | Active | LONDON | $154.2M |
| The London Cross-Cultural Learner Centre CA-E-M3K4-3EV4 | Registered charity | Active | LONDON | $125.5M |
| Gve Global Vision INC. CA-E-CP85-J39P | Federal corporation | Active | London | $113.9M |
| Echidna Holdings Corp. CA-E-HRKD-T0BV | Federal corporation | Dissolved | London | $106.8M |
| Ymca Of Southwestern Ontario CA-E-WPNJ-0RVQ | Registered charity | Former | LONDON | $89.4M |
| Western Maple Bio Resources Inc. CA-E-XDWC-CS47 | Federal corporation | Active | London | $59.8M |
| Let's Talk Science CA-E-RG9T-SJ0H | Registered charity | Active | London | $48.8M |
| South London Neighbourhood Resource Centre CA-E-VBDZ-EATA | Registered charity | Current | LONDON | $39.6M |
| Leads Employment Services London INC. CA-E-E97C-Y7NF | Registered charity | Former | LONDON | $32.6M |
| Upper Thames River Conservation Authority CA-E-VN15-3C13 | Registered charity | Current | LONDON | $24.2M |
| London Health Sciences Centre Research Inc. CA-E-M1GV-GQRC | Registered charity | Active | LONDON | $21.2M |
| Youth Opportunities Unlimited CA-E-ZVQG-TDXM | Registered charity | Current | LONDON | $20.4M |
| Lawson Research Institute CA-E-B8Z2-28K7 | Registered charity | Active | LONDON | $17.5M |
| London Health Sciences Centre CA-E-S4X9-B62Q | Registered charity | Current | LONDON | $16.9M |
| Fanshawe College Of Applied Arts & Technology CA-E-EG2H-90Q0 | Registered charity | Former | LONDON | $13.7M |
| Community Living London CA-E-HT1V-W4FS | Registered charity | Former | LONDON | $13.2M |
| London Regional Children's Museum CA-E-3TX9-CMVY | Registered charity | Current | LONDON | $12.1M |
| Hutton House Association For Adults With Disabilities CA-E-9W0E-X4V2 | Registered charity | Current | LONDON | $10.6M |
| Global Vision CA-E-SE93-X32G | Registered charity | Active | LONDON | $9.0M |
| Carrefour Communautaire Francophone De London CA-E-K5DK-2QSK | Registered charity | Former | LONDON | $7.1M |
| A-r Business Machines INC. CA-E-H6G0-SAFS | Federal corporation | Inactive | LONDON | $6.3M |
| Carolinian Canada Coalition CA-E-2MMN-5PJF | Registered charity | Active | London | $5.8M |
| St. Joseph Chaldean Catholic Church CA-E-KS73-2NQK | Registered charity | Active | London | $5.7M |
| Goodwill Industries-essex Kent Lambton INC. CA-E-Y831-AV5H | Registered charity | Current | LONDON | $5.3M |
| Museum London Foundation CA-E-024E-BF2H | Registered charity | Dissolved | LONDON | $4.3M |
| Boys' & Girls' Club Of London Foundation CA-E-AVHF-67E3 | Registered charity | Active | LONDON | $2.7M |
| London And Middlesex Heritage Museum CA-E-YFZX-M4J0 | Registered charity | Current | LONDON | $2.4M |
| Goodwill Industries Ontario Great Lakes CA-E-HG3R-P5T3 | Registered charity | Former | LONDON | $1.5M |
| Reforest London CA-E-NM05-N8N4 | Registered charity | Former | LONDON | $1.2M |
| Museum Of Ontario Archaeology CA-E-VXZ5-707K | Registered charity | Former | LONDON | $1.1M |
| London Environmental Institute CA-E-QV2P-7DFM | Registered charity | Active | London | $988K |
| West Park Baptist Church CA-E-NQX6-E2F6 | Registered charity | Active | LONDON | $911K |
| Thames Talbot Land Trust CA-E-KB30-VY77 | Registered charity | Active | LONDON | $808K |
| Forest City Film Festival CA-E-B47X-M7KV | Registered charity | Active | London | $392K |
| St. Joseph's Health Care London CA-E-B7G2-XQAQ | Registered charity | Current | LONDON | $339K |
| London Symphonia CA-E-S1MF-808D | Registered charity | Active | London | $300K |
| Mission Services of London Foundation CA-E-E16S-12AG | Registered charity | Active | LONDON | $251K |
| The 1st Hussars Cavalry Fund CA-E-KWQR-R6TC | Registered charity | Active | London | $195K |
| Muslim Wellness Network Charitable Organization CA-E-3AJ4-FRY3 | Registered charity | Active | London | $128K |
| Compassionate Community Care CA-E-H1ZS-1YF7 | Registered charity | Active | London | $97K |
| Chabad at Western CA-E-VX28-JVXP | Registered charity | Active | London | $96K |
| Summerside Community Church Fellowship Baptist CA-E-EWBM-9KFX | Registered charity | Active | LONDON | $86K |
| Alice Saddy Foundation CA-E-6THP-1FP0 | Registered charity | Active | London | $77K |
| Westview Baptist Church Of London CA-E-A68G-2JJC | Registered charity | Active | LONDON | $60K |
| Northern Bridge Community Partnership CA-E-R0SG-AVVA | Registered charity | Dissolved | London | $59K |
| The Sunshine Foundation of Canada CA-E-NJR0-JHJX | Registered charity | Active | London | $48K |
| Concussion Legacy Foundation (Canada) Inc. CA-E-BYYY-EE6H | Registered charity | Inactive | London | $43K |
| Mosaic Intercultural Church London CA-E-7A6R-RSTS | Registered charity | Active | London | $36K |
| Village Green Community Church CA-E-4EFJ-57M5 | Registered charity | Active | LONDON | $34K |
| Type Diabeat It CA-E-8JPP-QP38 | Registered charity | Active | London | $31K |
| The Gathering Place and Revival Centre CA-E-8YH5-PKAB | Registered charity | Active | LONDON | $18K |
| London Community Dental Alliance CA-E-NKC4-ADEE | Registered charity | Active | London | $16K |
| St.joseph's - Hospice Of London CA-E-33VD-BD31 | Registered charity | Active | LONDON | $14K |
| Impact Church London CA-E-6VXA-HMHX | Registered charity | Active | London | $14K |
| Community Counselling Centre of London CA-E-8YYP-QMWD | Registered charity | Active | London | $11K |
| Teen Challenge Canada INC. CA-E-3DFC-F9B1 | Registered charity | Active | London | $9K |